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• In addition, this patient also had polycythemia, doubtless secondary to high-dose testosterone.

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Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Review Of The Literature

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In addition, the info available within the literature doesn’t account for the steroid type or dose, as neither could also be recognized. Patients additionally could additionally be taking concomitant stimulants, similar to ephedra, which might confound data and the potential for antagonistic events. It is probably going that the frequency of cardiac occasions is underreported in the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which embrace greater than 30 natural and artificial derivatives of testosterone, could cause a large spectrum of scientific sequalae.

However, testosterone in physiologic doses could even be beneficial in patients with angina , have larger ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood circulate in males with established coronary artery illness . Therefore, an interplay of endogenous factors of the patient’s threat profile in addition to the testosterone dosing may be problems with whether or not opposed occasions happen. Erythrocytosis has been reported as a potential impact of testosterone, which may be helpful in sufferers with anemia. The greatest danger of erythrocytosis occurs with injectable forms of testosterone in contrast with transdermal preparations, particularly in supraphysiologic doses. An increase of as a lot as 44% of the baseline hematocrit has been reported . Moreover, testosterone has been used in the therapy of reduced muscle mass and bone density in addition to anemia.